The search for effective treatments for the new coronavirus infection SARS-CoV-2, which causes COVID-19, has led to the introduction of drugs used to treat other diseases into treatment regimens.
FDA-approved drugs such as ivermectin may be given off-label if the doctor determines they are medically appropriate for the patient. The FDA gives doctors the freedom to prescribe and treat drugs they think are best for the patient’s benefit.
Thus, the efficacy and safety profile of drugs based on ivermectin (Stromectol) was analyzed, including the experience of their use in clinical trials conducted during the COVID-19 pandemic. The anti-parasite drug ivermectin reduces the amount of viral RNA by 93% 24 hours after being added to cell culture in vitro, and by 99% after 48 hours.
STROMECTOL 3 mg, 6 mg, 12 mg
Active ingredient: Ivermectin
Available in a package of 8, 14, 20, 30, and 40 tablets.
Ivermectin is a broad-spectrum antiparasitic agent. It is used for the treatment of onchocerciasis, strongylosis, and other helminthiases, as well as for the treatment of scabies. In 2020, scientists brought international attention to ivermectin as a potential drug for COVID-19.
It is important to note that several peer-reviewed controlled clinical trials have been published worldwide that indicate the effectiveness of Ivermectin in the prevention and treatment of COVID-19.
Prophylactic use of Ivermectin by health care workers who are in constant contact with patients infected with coronavirus reduces the risk of symptomatic (i.e. severe) course of COVID-19 by 75%. This is the result of a study conducted with more than 500 healthcare professionals. The study is titled « Ivermectin as a method for pre-exposure prophylaxis of SARS-CoV-2 in healthcare workers. » Health workers received Ivermectin orally every week at a dose of 0.2 mg/kg.
Ivermectin is effective against all variants of the COVID-19 virus. Ivermectin prevents the viral protein from entering the nucleus of the infected cell, thereby disrupting the viral replication cycle. It becomes impossible to synthesize viral RNA and the emergence of many new viral particles.
Based on the relationship between the virus and the host cell, the main task of the virus is to enter the cell and actively multiply there. The first direction – prevention of fusion of the viral envelope and the cell membrane of the host cell – can be achieved through the use of drugs related to the mechanism of action as fusion inhibitors. The second direction – the effect on viral replication and inhibition of viral RNA synthesis – can be implemented using drugs that are related in their mechanism of action to inhibitors of viral RNA polymerase.
At the same time, the effectiveness of antiviral treatment depends on the speed of its administration: as early as possible, when the first symptoms appear (preferably within the first 24 hours of the disease, at the latest 48 hours after its onset).
WHO continues to explore the possibilities of combination antiviral therapy for patients with COVID-19 based on the analysis of the mechanism of action of antiviral drugs within the framework of a medical hypothesis.
There are many questions about treating COVID-19 with ivermectin: “Can ivermectin really prevent and treat all phases of COVID-19 disease? “.
Since its inception 40 years ago, Ivermectin has already demonstrated its effectiveness and eliminated the « pandemic » of parasitic diseases on several continents. It is for these effects that the creators of ivermectin were awarded the 2015 Nobel Prize in Medicine.
More recently, the powerful antiviral and anti-inflammatory properties of ivermectin have been identified. Research shows that one of its antiviral properties is that it binds strongly to the spike protein, preventing the virus from entering the cell. These effects, along with their ability to control inflammation, explain the positive test results.
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Considering that Stromectol (Ivermectin) has 5 different mechanisms of action against coronaviruses, the drug is effective in different variants of the virus. The powerful antiviral drug works and the effectiveness of ivermectin has been proven in many studies.
The discovery of ivermectin in 1975 was awarded the 2015 Nobel Prize in Medicine for its global impact in reducing onchocerciasis (river blindness), lymphatic filariasis, and scabies in endemic regions of Central Africa, Latin America, India, and Southeast Asia. It has since been included in the WHO list of essential medicines, which currently have over 4 billion doses.
Many studies report a low incidence of side effects, most of which are mild, transient, and largely related to the body’s inflammatory response to parasite death, including itching, rash, swollen lymph nodes, fever, and headaches.
Side effects of ivermectin
According to the reference pharmaceutical standard Lexicomp, the only contraindicated drugs for the use of ivermectin are the simultaneous administration of tuberculosis and cholera vaccines. Another caution is that immunocompromised or organ transplant patients taking calcineurin inhibitors such as tacrolimus, cyclosporine, or the immunosuppressant sirolimus should closely monitor drug levels while taking ivermectin, as there are interactions that may affect these levels.
Can I use Ivermectin if I am pregnant or breastfeeding?
According to current research, ivermectin prophylaxis is not recommended during pregnancy, especially during the first trimester. Ivermectin prophylaxis is also not recommended if you are trying to get pregnant. In the case of ivermectin, this is a risk-benefit decision that you should discuss with your healthcare provider. Teratogenicity has been found in animal studies with a HIGH dose of ivermectin. If a pregnant woman becomes ill with Covid-19 and has moderate or severe symptoms, the decision to use ivermectin should be made by the mother and physician. Breastfeeding is currently not recommended if the mother has been taking ivermectin for at least one week after stopping ivermectin, based on the limited data available.
Buy Ivermectin without a prescription
Ivermectin may be prescribed for you if your doctor determines it is medically appropriate. Physicians have the right to prescribe medications that are best in the best interest of the patient. The practice of prescribing drugs « off label » is widespread: one in five prescriptions is for off-label use. In the marketplace, prescriptions are written so often because there may not be an approved drug for a particular disease or health condition.
Importantly, several published and peer-reviewed clinical trials conducted around the world indicate the effectiveness of ivermectin in the prevention and treatment of COVID-19.
Good medical practice and the best interests of the patient require physicians to use legally available drugs, biologics and devices in accordance with their knowledge. Doctors can prescribe whatever they want as long as they feel well-informed and base their decision on sound medical evidence. However, you should note that individual institutions are free to set their own appointment standards if they so choose.
Save time and money by buying medicines online without a prescription. This will help you stay healthy by purchasing the most appropriate dosage forms. The online pharmacy will put you in touch with a qualified pharmacist who will help you complete your order quickly and safely. Online pharmacies offer their customers from all over the world very high-quality medicines, and excellent service at very affordable prices. The system for buying medicines via the Internet in a pharmacy is very convenient – it allows you to place an order without calling the operator. Simply select the product by placing it in the basket, then complete the checkout on the payment page of the electronic payment system.